Description
Tranexamic acid competitively inhibits activation of plasminogen(via binding to the kringle domain), thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII. Tranexamic acid also directly inhibits plasmin activity, but higher doses are required than are needed to reduce plasmin formation.
Indication
Tranexamic acid is indicated for the treatment of: – Hemorrhage or risk of hemorrhage in increased fibrinolysis or fibrinogen lysis .
Used For
Hemorrhage
Dosage
Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:
- For heavy menstrual bleeding (menorrhagia)- Take 1 tablet of Tranexamic Acid 250mg 3 times a day, ideally at mealtimes to reduce stomach upset.
- For thrombocytopenia (low platelet count)- The dose will depend on the severity of your condition and your doctor’s assessment. The typical starting dose is 1g (1,000mg) daily, divided into 3 smaller doses of 333mg taken at mealtimes. Your doctor may adjust this dose depending on your response and tolerance.
- For dental surgery- The recommended dose is 1 tablet of Tranexamic Acid 250mg taken 2 hours before surgery, followed by another tablet after an hour, and then a third tablet 2 hours after the surgery. This regimen helps reduce the risk of bleeding during and after the procedure.
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