CALIPTROL 40mg TAB 10s

349.00

CALIPTROL 40 mg contains Atorvastatin, a statin used to lower cholesterol and triglyceride levels in the blood. It helps reduce the risk of heart attack and stroke by lowering LDL (“bad”) cholesterol and raising HDL (“good”) cholesterol.

Taken once daily, with or without food, CALIPTROL is commonly prescribed for high cholesterol, mixed dyslipidemia, and cardiovascular risk prevention. Regular monitoring of liver function and lipid levels is recommended. Not suitable during pregnancy or breastfeeding.

 

Description

Product Overview:
CALIPTROL 40 mg Tablet contains Atorvastatin calcium, a member of the statin class of medications (HMG-CoA reductase inhibitors), used primarily to lower elevated levels of cholesterol and triglycerides in the blood. Atorvastatin works by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver. By reducing low-density lipoprotein cholesterol (LDL-C), total cholesterol, and triglycerides while modestly increasing high-density lipoprotein cholesterol (HDL-C), CALIPTROL helps reduce the risk of cardiovascular events such as heart attack and stroke.

 

Therapeutic Class:
HMG-CoA reductase inhibitor (Statin)

Active Ingredient:
Atorvastatin Calcium equivalent to Atorvastatin 40 mg

 

Indications:

  • Primary hypercholesterolemia (heterozygous familial and non-familial)
  • Combined (mixed) dyslipidemia
  • Homozygous familial hypercholesterolemia (as an adjunct to other lipid-lowering treatments)
  • Prevention of cardiovascular disease in patients at high risk, including those with diabetes or other risk factors
  • Reduction of total cholesterol, LDL-C, apolipoprotein B, and triglycerides; and to increase HDL-C in patients with dyslipidemia

 

Key Benefits:

  • Effectively lowers LDL-C (“bad cholesterol”) and triglycerides
  • Modestly increases HDL-C (“good cholesterol”)
  • Reduces the risk of cardiovascular morbidity and mortality
  • Once-daily dosing for convenience and adherence
  • Can be used alone or in combination with other lipid-lowering therapies

 

Dosage and Administration:

  • Recommended Dose: 10–80 mg once daily.
  • Typical Starting Dose: 10 or 20 mg once daily, adjusted at intervals of 4 weeks or more.
  • Maximum Dose: 80 mg per day.
  • Should be taken at any time of the day, with or without food.

 

Contraindications:

  • Hypersensitivity to Atorvastatin or any excipients
  • Active liver disease or unexplained persistent elevations of hepatic transaminases
  • Pregnancy and lactation
  • Women of childbearing potential not using appropriate contraception

 

Warnings and Precautions:

  • Monitor liver function before and during treatment.
  • Use with caution in patients with a history of liver disease, alcoholism, or renal impairment.
  • Rare risk of myopathy or rhabdomyolysis, especially when used with other lipid-lowering agents.
  • Monitor for signs of muscle pain, tenderness, or weakness.

 

Adverse Effects:

Common:

  • Headache
  • Myalgia (muscle pain)
  • Diarrhea
  • Arthralgia
  • Nausea

Rare but Serious:

  • Elevated liver enzymes
  • Rhabdomyolysis
  • Hepatitis
  • Pancreatitis
  • Hypersensitivity reactions

 

Drug Interactions:

  • Increased risk of muscle toxicity with concurrent use of fibrates, niacin, cyclosporine, or certain antibiotics (e.g., clarithromycin).
  • May interact with anticoagulants (e.g., warfarin), leading to increased bleeding risk.
  • Use caution when combining with drugs that affect CYP3A4 metabolism (e.g., ketoconazole, HIV protease inhibitors).

Storage:

  • Store below 25°C (77°F)
  • Protect from moisture and direct sunlight
  • Keep out of reach of children

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