Deltacortil EC (5mg) 100 Tablets

Description

Description 

Glucocorticoid steroid prednisolone is renowned for its anti-inflammatory properties. It achieves this by interacting with the phospholipase A2 protein found in cell membranes, inhibiting the release of prostaglandins and leukotrienes, which are chemicals that fuel and amplify the body’s inflammatory response. Not only that, but prednisolone also acts as an immune system suppressant by increasing blood levels of glucocorticoids. These chemicals hinder the release of cytokines, which are responsible for signaling the immune system to ignite and intensify inflammation. By curbing the inflammatory response, prednisolone serves as an effective treatment for various inflammatory conditions like rheumatoid arthritis, severe asthma, and disseminated lupus erythematosus. However, it is crucial to weigh the benefits of this drug with its potential side effects, which can be very serious due to its immune suppression capabilities. Prednisolone is often prescribed carefully and sparingly to manage these conditions. 

Ingredients 

Prednisolone 

Drug Class 

Corticosteroid 

Dosage Form 

Tablet 

Uses 

Unveiling its multifaceted uses and transformative applications as follows: 

Treat various skin conditions 

Relief of symptoms of asthma 

Help cope with intense allergic reactions 

Treat flare-ups of inflammatory bowel disease 

Slow damage to joints from rheumatoid arthritis 

Treat polymyalgia rheumatica 

Reduce inflammation caused by certain cancers 

Prevent or reduce sickle cell crisis 

Treat eye pain and swelling following eye surgery 

Help prevent transplant rejection 

Prednisolone 5mg is a veterinary medicine used for various inflammatory and autoimmune conditions in animals. 

Dosage 

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is: 

For seasonal allergies- Prescribed 1mg-2mg per day, depending on symptom severity. 

For skin conditions- Prescribed 0.5mg-1mg per day, for conditions such as eczema or psoriasis. 

For respiratory conditions- Standard starting dose of 0.5mg-2mg per day, adjusted based on symptom control and adverse effect severity for conditions such as asthma or bronchitis. 

For autoimmune conditions- Initial dose of 5mg-10mg per day, with severe flare-ups requiring higher doses of 20mg per day, for conditions such as rheumatoid arthritis or lupus. 

For prednisolone dosing- Adhere to medical professional instructions and do not adjust dosage without consultation. 

In case of Overdose 

Overdosing on prednisolone would require immediate medical attention and monitoring, with treatment varying depending on individual factors and overdose severity. The medically supervised symptomatic treatment provides relief from adverse effects like nausea, vomiting, diarrhea, or abdominal pain. Doctors may also recommend a gradual reduction in the steroid dose, known as steroid tapering, to prevent withdrawal symptoms and restore hormonal balance. Severe side effects resulting from overdose may include hypertension, hyperglycemia, gastrointestinal issues, and psychological symptoms like mood swings, aggression, and irritability. Prednisolone’s prolonged use leads to bone density loss, and doctors may recommend calcium and vitamin D supplements to counteract this effect.Recovery psychology also plays a crucial role in overdose situations. Steroid use can lead to mood changes, anxiety, and depression, referring patients to mental health professionals for emotional evaluations and supportive care. 

Missed Dose 

If you miss a dose of prednisolone 5mg, it is crucial to take it as soon as possible. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and continue with your regular dosing schedule. This is to prevent overdosing. It is imperative to follow the instructions provided by your physician or pharmacist, and if you have any further questions or concerns, be sure to consult with them. Overdosing or missing doses can be detrimental to your health and may require immediate medical attention. 

How To Use 

Prednisolone is a medication that reduces inflammation and treats several conditions, including arthritis, asthma, and skin problems. It is essential to follow your doctor or pharmacist’s medication guide and read it each time you get a refill. If you have questions, ask your doctor or pharmacist. Prednisolone 5mg tablets are usually taken once daily. Your doctor will determine the dosage based on your condition and response to the treatment to reduce the risk of side effects. You may take the tablet with food or milk if it helps avoid stomach upset. However, it is best to take it as directed by your doctor. You may need other medications to manage the side effects of prednisolone, such as prescription heartburn medication or antibiotics. While taking prednisolone, it is crucial to monitor your blood pressure and inform your doctor if you notice any changes. Avoid alcohol, as it can increase the chances of adverse effects. If you have allergies or other medical conditions, you must inform your doctor as prednisolone may cause severe side effects in some cases. Your doctor may recommend regular eye exams during treatment to monitor any changes. If you are pregnant or nursing, it is essential to consult your healthcare provider before taking prednisolone. If you miss a dose, take it as soon as possible. If it is near the time of the next dose, skip the missed dose and take your regular dose. Do not double up to make up for the missed dose. It is important to follow instructions provided by your healthcare provider. With prednisolone, it is crucial to follow the medication guide and your doctor’s advice as it helps to manage side effects and ensure the medication is effective. 

When Not to Use 

Discerning instances where this medication may not be appropriate: 

Active infection 

Peptic ulcer 

Psychiatric condition 

Kidney disease 

High blood pressure 

Side Effects 

Unraveling the side effects lurking behind this medications are as follows: 

Increased risk of infections 

Acne, scaliness, rash, or skin pigmentation 

Slowdown of healing wounds 

Swelling, stiffness, or pain in joints 

Blurry vision or other visual disturbances 

Vomiting or nausea Less commonly, people may also experience 

• Gonadal dysfunction issues with sex hormones

High blood pressure 

Increased risk of diabetes 

Muscle weakness 

Liver damage 

Bloating 

Diarrhea 

Increased appetite 

Precautions & Warnings 

Patients should take the following precautions and warnings into account before using this medication: 

Individuals with a personal or family history of severe affective disorders (e.g., steroid psychosis, depressive or manic-depressive illness) need special caution. 

Patients with a history of tuberculosis (TB), latent TB, or tuberculin reactivity, as well as those with known or suspected Strongyloides infection, should be cautious. 

Diabetes mellitus patients or those with a family history of diabetes should be monitored. 

Those with gastrointestinal diseases (e.g., diverticulitis, ulcerative colitis, active or latent peptic ulcer, recent intestinal anastomoses, abscesses, or pyogenic infections) should be cautious. 

Patients with glaucoma or a family history of glaucoma, cataracts, or a history of ocular herpes simplex need special consideration. 

Hypertension, congestive heart failure (CHF), or a recent myocardial infarction (MI) with a risk of rupture are significant risk factors to consider. 

Existing or potential osteoporosis (e.g., postmenopausal women) or seizure disorders require caution. 

Those with systemic sclerosis, Cushing’s disease, steroid myopathy, myasthenia gravis, thromboembolic disorders, Duchenne’s muscular dystrophy, or thyroid disease should be closely monitored. 

Patients under unusual stress (e.g., surgery, trauma, intercurrent illness) need to take special care. 

Exposure to individuals with chickenpox or measles should be avoided. 

Avoid abrupt withdrawal during long-term therapy, as it may mask the signs of infection. 

Use in active TB cases should be limited to fulminating or disseminated TB. 

Patients with renal or hepatic impairment, including cirrhosis, need to be closely monitored. 

Caution is needed for children and elderly individuals. 

Special attention is required for pregnancy and lactation. 

Drug Interactions 

Drug interactions with prednisolone include: 

Anticoagulants (e.g., warfarin) (may enhance the effect of anticoagulants) 

NSAIDs (e.g., ibuprofen) (increased risk of gastrointestinal bleeding or ulceration) 

Antidiabetic medications (e.g., insulin, metformin) (may increase blood glucose levels) 

Live vaccines (e.g., MMR) (prednisolone may reduce vaccine efficacy) 

CYP3A4 inhibitors (e.g., ketoconazole) (may increase prednisolone levels) 

CYP3A4 inducers (e.g., rifampin) (may decrease prednisolone levels) 

Antihypertensives (e.g., ACE inhibitors) (prednisolone may cause fluid retention and hypertension) 

Storage/Disposal 

Prednisolone is a prescription steroid that must be taken orally, either in tablet or liquid form. Since it is a medication, it is important that it is stored properly to ensure its efficacy and prevent degradation. Storage of prednisolone must be in a cool, dry place away from any form of heat or light. The ideal temperature to store prednisolone is between 36-77°F (2-25°C). It must also be kept away from freezing temperatures and must not be kept in a car or any place with direct sunlight. Exposure to heat causes it to degrade and renders it ineffective. For safety purposes, prednisolone must remain in its original container and kept tightly closed. It should also be kept out of the reach of children. Each formulation may have different storage instructions so it is important to adhere to the instructions on the label or as instructed by your healthcare provider. By ensuring proper storage, you maintain the integrity and potency of the medication, allowing it to effectively treat symptoms when taken as prescribed. 

Laboratory Screening 

Prednisolone is a powerful corticosteroid medication prescribed to treat various inflammatory conditions like rheumatoid arthritis, lupus, allergies, asthma, and multiple sclerosis. When taking this medication, it is crucial to undergo periodic laboratory testing to monitor your overall health and ensure the safety of your vital organs, such as your kidneys and liver. Your doctor will individually tailor the tests based on your specific condition, dosage, and the duration of treatment. To begin with, frequent blood tests are often recommended to monitor essential elements of your blood composition, including red and white blood cells, platelet count, and blood pressure. These tests can help uncover any underlying conditions and evaluate whether the medication is influencing your blood levels. Additionally, frequent kidney function tests are essential, especially with higher doses or prolonged use, to assess kidney function by measuring creatinine and potassium levels and monitoring for any signs of kidney injury. Since prednisolone is processed by the liver, liver function tests are often ordered to screen for signs of liver damage, including measuring liver enzymes and bilirubin levels in the blood. For conditions affecting the eyes, such as ocular inflammation, regular eye exams are essential to monitor structural and functional changes. Notably, long-term prednisolone use can have implications for bone health, leading to osteoporosis or bone loss, necessitating bone density tests to monitor changes in bone mineral density. Furthermore, people with diabetes or prediabetes should monitor their blood sugar levels closely as prednisolone can cause elevated blood sugar levels. Your doctor will recommend specific tests based on your individual needs and adjust the testing frequency based on the results. Remember, comprehensive lab testing, combined with proactive medical care, significantly reduces the risks associated with long-term prednisolone use.