Enoxabid Tablet 400mg (2×10s)

Description

Enoxabid 400mg Tablets

Pack Size:

2 x 10 Tablets (Total 20 tablets per pack, in two blister strips)

Generic Name:

Enoxacin

Pharmacological Class:

Fluoroquinolone Antibiotic

Product Description:

Enoxabid Tablet 400mg is a broad-spectrum antibacterial agent containing Enoxacin, a second-generation fluoroquinolone. Each tablet delivers 400mg of Enoxacin, formulated for oral administration. It is primarily indicated for the treatment of a wide range of bacterial infections, particularly those affecting the urinary tract, respiratory system, and genital tract.

The 2x10s packaging configuration ensures patient convenience, dosing compliance, and product protection from environmental factors.

Indications / Uses:

Enoxabid 400mg is indicated for the treatment of infections caused by susceptible strains of bacteria, including:

• Urinary Tract Infections (UTIs)
• Chronic bacterial prostatitis
• Uncomplicated gonorrhea
• Chlamydial infections (as adjunct therapy)
• Skin and soft tissue infections
• Respiratory tract infections (off-label and only when no safer alternatives exist)

Note: Use is limited to specific cases due to safety concerns with fluoroquinolones.

Dosage and Administration:

• Adults: 400 mg every 12 hours, depending on the severity and site of infection
• Administration: Swallowed whole with water, preferably on an empty stomach
• Duration: Typically, 5–10 days; follow physician’s guidance

Avoid concomitant use with dairy, iron, or antacids to ensure proper absorption.

Mechanism of Action:

Enoxacin inhibits the bacterial enzymes DNA gyrase and topoisomerase IV, essential for DNA replication and cell division. Its bactericidal action effectively halts bacterial proliferation.

Side Effects:

Common:

• Gastrointestinal upset (nausea, diarrhea)
• Dizziness
• Headache
• Rash

Serious (rare but notable):

• Tendonitis or tendon rupture
• CNS effects (seizures, agitation)
• Peripheral neuropathy
• Photosensitivity
• QT prolongation

Warnings and Precautions:

• Avoid in pregnancy, breastfeeding, and children under 18 (risk of cartilage damage)
• Caution in elderly patients, particularly with corticosteroid use
• Renal impairment may require dosage adjustment
• Avoid prolonged sun exposure or use sunscreen due to risk of photosensitivity
• Discontinue if tendon pain, confusion, or skin reactions occur

Drug Interactions:

• Decreased absorption with antacids, calcium, iron, magnesium, or zinc
• Increased risk of seizures with NSAIDs
• May potentiate the effects of theophylline and warfarin

Contraindications:

• Known hypersensitivity to Enoxacin or other fluoroquinolones
• Epilepsy or seizure disorders
• Pediatric patients and pregnant/lactating women

Packaging and Storage:

• Blister Pack: 2 strips of 10 tablets (total 20 tablets)
• Storage Conditions: Store below 25°C, protect from light and moisture
• Shelf Life: As per manufacturer’s labeling (typically 2–3 years from manufacturing date)

Regulatory Classification:

• Prescription Only Medicine (POM)
• Requires diagnosis and prescription from a registered healthcare provider

Note to Pharmacists and Patients:

Due to the potential for serious side effects, Enoxabid should only be used when clearly indicated and when safer antibiotics are not appropriate. Always follow prescribed dosage and complete the full course of therapy even if symptoms improve early.