Poze 45mg Tab 14’s

Description

Composition:
Each tablet contains:

• Pioglitazone Hydrochloride 45 mg

Description:
Poze 45 mg is an oral antidiabetic medication belonging to the thiazolidinedione class. It is primarily prescribed to manage type 2 diabetes mellitus by improving the body’s sensitivity to insulin. By enhancing insulin action, Poze helps lower blood glucose levels effectively in patients who do not achieve adequate control with diet and exercise alone.

Indications:

• Management of type 2 diabetes mellitus
• Used as monotherapy or in combination with other antidiabetic agents, including metformin and sulfonylureas
• Suitable for patients requiring improved insulin sensitivity

Dosage and Administration:
The usual recommended dose is one 45 mg tablet once daily, taken with or without food. Dosage adjustments should be made based on patient response and tolerability, under medical supervision.

Mechanism of Action:
Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ), which regulates the transcription of insulin-responsive genes involved in glucose and lipid metabolism. This action improves insulin sensitivity in adipose tissue, muscle, and the liver.

Warnings and Precautions:

• Use with caution in patients with heart failure or risk factors for fluid retention
• Monitor liver function periodically
• Not indicated for type 1 diabetes or diabetic ketoacidosis
• May cause weight gain and edema
• Inform your doctor about any history of bladder cancer or heart problems

Side Effects:
Common side effects include weight gain, edema, headache, and upper respiratory tract infections. Rare but serious side effects may include heart failure, liver toxicity, and bladder cancer.

Storage:
Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.