RYBIO 400mg CAP 10s

Description

RYBIO 400mg Capsule (Ribavirin) is an antiviral medication used to treat chronic hepatitis C in combination with other antiviral agents. Ribavirin works by inhibiting viral replication, thereby reducing the amount of virus in the body.

🩺 Indications

RYBIO 400mg Capsule is indicated for:

• Chronic Hepatitis C infection
• In combination with other antiviral agents for the treatment of chronic hepatitis C

⚙️ Mechanism of Action

Ribavirin is a nucleoside analog that interferes with viral RNA synthesis and capping, inhibiting viral replication. It is metabolized intracellularly to its active form, ribavirin triphosphate, which incorporates into viral RNA, leading to lethal mutagenesis and inhibition of viral replication.

💊 Dosage and Administration

• Chronic Hepatitis C:
  • Adults with body weight under 65 kg: 400 mg twice daily
  • Adults with body weight 65–85 kg: 400 mg in the morning and 600 mg in the evening
  • Adults with body weight over 85 kg: 600 mg twice daily
• Administered orally with food to enhance absorption.

⚠️ Precautions

• Pregnancy: Ribavirin is contraindicated during pregnancy due to the risk of birth defects or death of the unborn baby. Both male and female patients must use effective contraception during treatment and for specified periods after discontinuation.
• Anemia: May cause a significant drop in red blood cell count, leading to anemia. This condition has been associated with worsening heart problems and, in rare cases, can cause heart attack and death.
• Liver Disease: Use with caution in patients with liver disease.
• Kidney Disease: Adjustments may be necessary for patients with renal impairment.

💊 Side Effects

Common side effects include:

• Fatigue
• Headache
• Nausea
• Anemia
• Rash
• Insomnia

🛡️ Warnings

• Pregnancy: Ribavirin is contraindicated during pregnancy. Both male and female patients must use effective contraception during treatment and for specified periods after discontinuation.
• Anemia: May cause a significant drop in red blood cell count, leading to anemia. This condition has been associated with worsening heart problems and, in rare cases, can cause heart attack and death.