Teph Insta 40 Capsules 40Mg (1 Strip = 7 Capsules)

244.65

Generics 

Omeprazole + Sodium Bicarbonte 

Used For 

Gastroesophageal Reflux Disease 

How it works 

Omeprazole reduces gastric acid secretion through a unique mechanism of action. Omeprazole belongs to a class of anti-secretory compounds – the substituted benzimidazoles that do not exhibit anti-cholinergic or H2 histamine antagonistic properties. It inhibits secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium adenosine triphosphatase (H+/K+ATPase), the proton pump of the gastric parietal cell. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus. 

 

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Description

Teph Insta Specification 

Requires Prescription (YES/NO) 

Yes 

Generics 

Omeprazole + Sodium Bicarbonte 

Used For 

Gastroesophageal Reflux Disease 

How it works 

Omeprazole reduces gastric acid secretion through a unique mechanism of action. Omeprazole belongs to a class of anti-secretory compounds – the substituted benzimidazoles that do not exhibit anti-cholinergic or H2 histamine antagonistic properties. It inhibits secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium adenosine triphosphatase (H+/K+ATPase), the proton pump of the gastric parietal cell. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus. 

Teph Insta Usage And Safety 

Dosage 

Omeprazole + Sodium Bicarbonte 

Side Effects 

Common : Central and peripheral nervous system: Headache. Gastrointestinal: Diarrhea, constipation, abdominal pain, nausea/vomiting and flatulence.Uncommon : Central and peripheral nervous system: Dizziness, paraesthesia, somnolence, insomnia and vertigo.Hepatic: Increased liver enzymesSkin: Rash and/or pruritis, urticariaOther: MalaiseRare : Central and peripheral nervous system: Reversible mental confusion, agitation,aggression, depression and hallucinations, predominantly in severely ill patients.Endocrine: Gynecomastia 

Drug Interactions 

Ketoconazole and itraconazole , diazepam, citalopram, imipramine, clomipramine, phenytoin , Atazanavir , Digoxin , Clopidogrel , posaconazole, erlotinib , Saquinavir , Tacrolimus , Methotrexate , clarithromycin , CYP2C19 or CYP3A4 or both (such as rifampicin and St John’s wort. 

Indication 

It (Omeprazole) is indicated in adults for the treatment of: Gastro-Esophageal Reflux Disease (GERD):- Treatment of erosive reflux esophagitis.- Long term management of patients with healed esophagitis to prevent relapse.- Symptomatic treatment of gastroesophageal reflux disease (GERD). 

When not to Use 

Omeprazole is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles. Omeprazole must not be used concomitantly with nelfinavir. 

Teph Insta Precautions 

Precaution 

Symptomatic response to therapy with omeprazole does not preclude the presence of gastric malignancy . 

Teph Insta Warnings 

Warning 1 

Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with omeprazole . 

Warning 2 

Sodium bicarbonate should be used with caution in patients with Bartter’s syndrome, hypokalemia, respiratory alkalosis, and problems with acid-base balance. Long- term administration of bicarbonate with calcium or milk can cause milk-alkali syndrome . 

Warning 3 

Omeprazole powder for oral suspension contains sodium in the form of sodium bicarbonate. This should be taken into consideration for patients on a sodium restricted diet . 

Teph Insta Additional Information 

Pregnancy category 

Always consult your physician before using any medicine. 

Storage (YES/NO) 

Store this medicine at room temperature, away from direct light and heat. 

 

 

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