Description
Description
Atenolol 25mg Tablet primarily works by selectively blocking beta-1 adrenergic receptors in the heart, which are responsible for the effects of catecholamines like norepinephrine and epinephrine. By blocking these receptors, atenolol inhibits the activation of a stimulatory G-protein, leading to decreased levels of cyclic AMP (cAMP) in cardiac cells. This reduction in cAMP results in reduced cardiac stimulation, causing a decrease in heart rate, myocardial contractility, and conduction velocity. Consequently, the heart requires less oxygen, and blood pressure is lowered due to reduced cardiac output and peripheral vascular resistance. This mechanism makes atenolol effective in managing hypertension and certain heart conditions by slowing the heart rate and reducing the workload on the heart.
Ingredients
Atenolol 25mg
Drug Class
Beta-blocker
Dosage Form
Tablet
Uses
The following are the uses of Atenolol 25mg Tablet:
Used for managing high blood pressure, helping to lower and control hypertension.
Used for treating angina, relieving chest pain and discomfort associated with heart problems.
Used to reduce the risk of future heart attacks or strokes, especially after a recent cardiac event.
Used to improve survival rates and heart function in patients with heart failure.
Used for controlling irregular heart rhythms, particularly in conditions like atrial fibrillation.
Used for relieving anxiety-related symptoms, especially physical manifestations like rapid heartbeat.
Used for supporting long-term heart health and preventing cardiovascular complications.
Used to manage certain thyroid-related issues, such as hyperthyroidism, by controlling heart rate.
Dosage
Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:
High blood pressure- 50–100 mg once daily or 250–500 mg once daily (for immediate-release tablets)
Angina- 50–100 mg once daily or 250–500 mg once daily (for immediate-release tablets)
Heart attack- 50 mg every 12 hours, up to 100 mg every 12 hours if not tolerated or uncontrolled CV disease, increasing by 50 mg every 12 hours every 2 weeks to a maximum of 300 mg/day
Abnormal heart rhythm- 50 mg every 12 hours or 100 mg every 12 hours if needed
Anxiety- 50 mg once daily; adjust dose based on response
In case of Overdose
In the case of an overdose of Atenolol 25mg Tablets, it is important to recognize the signs and symptoms, which may include severe dizziness, extreme fatigue, and a significantly slow heart rate. If an overdose is suspected, seek medical advice promptly. Quick action is vital, as the consequences can be severe, potentially leading to a dangerous drop in blood pressure and heart rate. Immediate medical attention should be sought to address the situation effectively.
Missed Dose
In the case of a missed dose of Atenolol 25mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, consult your healthcare professional for advice on how to safely resume your medication regimen. It is advisable to set reminders or alarms to help you remember to take your medication on time.
How To Use
To take Atenolol 25mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.
When Not to Use
Here are the conditions or situations when Atenolol 25mg Tablet should not be used:
Should not be used in patients with known allergy or hypersensitivity to Atenolol or other beta-blockers.
Contraindicated in patients with severe or uncontrolled heart failure.
Not suitable for individuals with very slow heart rates (bradycardia).
Should not be used in patients with cardiogenic shock.
Contraindicated in patients with severe blood circulation disorders in the limbs (severe peripheral vascular disease).
Not recommended for patients with uncontrolled asthma or severe chronic obstructive pulmonary disease (COPD).
Should not be used in patients with untreated pheochromocytoma.
Contraindicated during episodes of low blood sugar (hypoglycemia) in diabetic patients.
Should be avoided in patients with severe liver disease or impaired liver function.
Not suitable for patients with metabolic acidosis (a condition with high acid levels in the blood).
Side Effects
The side effects of Atenolol 25mg Tablet may include:
Fatigue and weakness
Dizziness or lightheadedness
Cold extremities (hands and feet)
Slow heart rate (bradycardia)
Impaired sexual function
Depression
Sleep disturbances
Gastrointestinal issues (nausea, diarrhea)
Precautions & Warnings
Following are the precautions and warnings for Atenolol 25mg Tablet:
Do not abruptly discontinue the medication; gradual reduction is advised to prevent adverse effects.
Patients with a history of heart problems, such as heart block, heart failure, or a slow heart rate, should use it with caution and under medical supervision.
Blood pressure and heart rate should be monitored regularly during treatment.
Not recommended for individuals with severe liver disease or asthma.
May cause dizziness; patients should avoid driving or operating machinery until they know how it affects them.
Elderly patients may be more sensitive to the effects, so lower doses are typically recommended.
Diabetic patients should monitor their blood sugar levels as Atenolol may mask the symptoms of low blood sugar.
Drug Interactions
Following are the drug interactions for Atenolol 25mg Tablet:
Concurrent use with other beta-blockers can result in additive effects and increased risk of bradycardia and hypotension.
Taking Atenolol with calcium channel blockers may cause excessive lowering of blood pressure and heart rate.
The effects of insulin and oral hypoglycemic drugs may be enhanced, leading to potential hypoglycemia.
Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the antihypertensive effects of Atenolol.
Rifampicin can decrease the levels of Atenolol, reducing its effectiveness.
Atenolol may increase the blood levels of lithium, leading to potential toxicity.
Antacids may reduce the absorption of Atenolol if taken simultaneously.
Use with Class I antiarrhythmic drugs (e.g., disopyramide) may lead to increased cardiac depression and heart block.
Food Interactions
Following are the food interactions for Atenolol 25mg Tablet:
Avoid excessive alcohol consumption as it can increase the risk of low blood pressure and may exaggerate the sedative effects of Atenolol, leading to dizziness and fainting.
Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of Atenolol, potentially increasing its levels in the blood and prolonging its effects.
Caffeinated beverages like coffee and tea might counteract the blood pressure-lowering effect of Atenolol, making it less effective.
A high-fiber diet is recommended as it can aid in reducing cholesterol levels, which is beneficial for those taking Atenolol for cardiovascular conditions.
Avoid salt substitutes containing potassium as Atenolol can increase potassium levels, and excessive potassium can lead to heart-related issues.
Maintain a balanced diet low in saturated fats and cholesterol to support overall cardiovascular health.
Always follow the dietary advice provided by your healthcare professional, especially if you have specific dietary restrictions or health conditions.
No significant food interactions directly impact Atenolol’s absorption, but certain foods may influence its effectiveness and side effects.
Storage/Disposal
Atenolol 25mg Tablets should be stored in a cool, dry place, preferably at room temperature, ensuring it remains below 25°C. Keep the tablets in their original container, tightly sealed, to maintain their integrity and protect them from moisture and light. It is crucial not to expose the medication to direct sunlight as it can degrade the active ingredients. Always check the expiration date, and never use the tablets beyond this date. When disposing of unused or expired tablets, do not throw them in the trash or flush them; instead, follow local guidelines for pharmaceutical waste disposal or consult a pharmacist for safe disposal methods. Keep the medication securely locked away from children and pets to prevent accidental ingestion.
Quick Tips, if any
Following are the quick tips for Atenolol 25mg Tablet:
Take the tablet as directed by your doctor, typically once daily at the same time each day.
Swallow the tablet whole with a glass of water, do not crush or chew.
It can be taken with or without food, but taking it with food may prevent stomach upset.
Avoid alcohol consumption as it may interfere with the medication’s effectiveness.
Do not suddenly stop taking this medication; gradually reduce the dose as advised by your doctor.
Regularly monitor your blood pressure and report any unusual symptoms to your doctor.
Store the tablets in a cool, dry place, away from direct sunlight and moisture.
Laboratory Screening
Atenolol is a prescription medication that serves multiple purposes. It can treat conditions such as high blood pressure, heart pain, and abnormal heart rhythm. While it is vital to measure your blood pressure regularly to ensure it remains stable, lab tests may be recommended to monitor your blood, kidney function, and electrolyte levels. These tests are crucial to ensure the safety and effectiveness of Atenolol and to monitor any potential side effects. Depending on your individual circumstances, your doctor or pharmacist may suggest specific tests to monitor your health while taking Atenolol. These may include blood tests that monitor blood cell count, cholesterol levels, and liver and kidney function. Kidney function tests, such as serum creatinine and blood urea nitrogen, may also be recommended. Additionally, electrolyte tests may be advised to monitor changes in levels such as potassium, sodium, and calcium. It is vital to speak with your healthcare provider about the appropriate lab tests necessary for your condition. Consistent monitoring of your blood pressure and appropriate lab testing can ensure that Atenolol is safe and effective for your specific needs.
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