Description
Norfloxacin is a quinolone carboxylic acid antibacterial agent for oral administration. Norfloxacin inhibits bacterial deoxyribonucleic acid synthesis and is bactericidal. At the molecular level, three specific actions have been attributed to norfloxacin in the inhibition of E.coli cells: 1. inhibition of the ATP-dependent DNA supercoiling reaction catalyzed by DNA gyrase, 2. inhibition of the relaxation of supercoiled DNA, 3. promotion of double-stranded DNA breakage.
Used For
Bacterial Infection
Indication
It is used to treat some bacterial infections, such as : Urinary tract infections (uncomplicated urinary tract infections including cystitis and complicated urinary tract infections) – Sexually transmitted diseases (uncomplicated urethral and cervical gonorrhea due to Neisseria gonorrhea) – Prostatitis (due to Escherichia coli) .
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