Description
Natrilix Sr Specification
Requires Prescription (YES/NO)
Yes
Generics
Indapamide
Used For
Hypertension
How it works
Indapamide is a non-thiazide sulfonamide with an indole ring, belonging to the diuretic family. At the dose of 2.5 mg per day it exerts a prolonged antihypertensive activity in hypertensive human subjects.
Natrilix Sr Usage And Safety
Dosage
Indapamide
Side Effects
Common : Raised skin rashes, allergic reactions, mainly dermatological, in subjects predisposed to allergic or asthmatic reactions ; Uncommon : Vomiting, red pinpoints on skin (purpura). Rare : Feeling of tiredness, headache, pins and needles (paraesthesia), dizziness, gastro-intestinal disorders (such as nausea, constipation), dry mouth ; Very rare : Changes in blood cells, such as thrombocytopenia (decrease in the number of platelets which causes bruising, contusions and nasal bleeding), leucopenia (decrease in white blood cells which may cause unexplained fever, soreness of the throat or other flu-like symptoms – if this occurs, and anaemia (decrease in red blood cells), increase of calcium in the blood, heart rhythm irregularities, low blood pressure, kidney disease, abnormal liver function .
Drug Interactions
Quinidine, hydroquinidine, disopyramide, amiodarone, sotalol. ibutilide, dofetilide, digitalis , tricyclic antidepressants, antipsychotic drugs, neurolepties) , bepridil , cisapride, diphemanll , sparfioxacin, moxifioxacin , halofantrine , pentamidine , mizolastine , ibuprofen or high doses of acetylsalicylic acid, angiotensin converting enzyme (ACE) Inhibilors , oral corticosteroids , stimulant laxatives, baclofen , potassium-sparing diuretics (amiloride, spironolactone, triamterene), metformin , iodinated contrast media (used for tests involving X-rays) , calcium tablets or other calcium supplements, ciclosporin , tacrolimus , tetracosactide .
Indication
This medicine is intended for the treatment of high blood pressure (hypertension).
When not to Use
Do not take : If you are allergic to indapamide or any other sulphonamide or to any of the other ingredients , film coated tablet , If you have severe kidney disease, If you have severe liver disease or suffer from a condition called hepatic encephalopathy (degenerative disease of the brain), If you have low potassium levels in your blood.
Natrilix Sr Precautions
Precaution
Cases of photosensitivity reactions have been reported with thiazides and thiazide-related diuretics . If photosensitivity reaction occurs during treatment, it is recommended to stop the treatment. If a re-administration of the diuretic is deemed necessary, it is recommended to protect exposed areas to the sun or to artificial UVA .
Natrilix Sr Warnings
Warning 1
Thiazides and related diuretics including indapamide have been shown to increase the urinary excretion of magnesium, which may result in hypomagnesaemia .
Warning 2
Monitoring of blood glucose is important in diabetics, in particular in the presence of hypokalaemia.
Warning 3
Hypovolaemia, secondary to the loss of water and sodium induced by the diuretic at the start of treatment causes a reduction in glomerular filtration. This may lead to an increase in blood urea and plasma creatinine. This transitory functional renal insufficiency is of no consequence in individuals with normal renal function but may worsen pre-existing renal insufficiency.
Natrilix Sr Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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