Description
Product Name: Rigix Tablets 10 mg
Dosage Form: Oral Tablet
Strength: 10 mg
Active Ingredient: Risedronate Sodium
Route of Administration: Oral
Description:
Rigix Tablets contain Risedronate Sodium, a potent bisphosphonate used to treat and prevent osteoporosis. It works by inhibiting bone resorption by osteoclasts, thereby increasing bone mineral density and reducing the risk of fractures. Rigix is commonly prescribed for postmenopausal women, men with osteoporosis, and patients receiving corticosteroid therapy who are at risk of bone loss.
Indications:
- Treatment and prevention of postmenopausal osteoporosis
- Treatment of osteoporosis in men
- Prevention and treatment of corticosteroid-induced osteoporosis
- Management of Paget’s disease of bone (depending on physician’s discretion)
Mechanism of Action:
Risedronate binds to hydroxyapatite crystals in bone and inhibits osteoclast-mediated bone resorption, leading to increased bone strength and reduced fracture incidence. It selectively targets areas of high bone turnover.
Dosage and Administration:
- Typically taken once daily or once weekly, depending on the prescribed regimen
- Taken orally with a full glass of water on an empty stomach, at least 30 minutes before the first food, drink, or medication of the day
- Patients should remain upright for at least 30 minutes after taking the tablet to minimize the risk of esophageal irritation
Storage:
Store at room temperature (15–30°C). Keep in a dry place away from light and moisture. Keep out of reach of children.
Warnings and Precautions:
- Not suitable for patients with esophageal abnormalities or inability to sit/stand upright
- Use with caution in renal impairment
- Potential side effects include gastrointestinal irritation, musculoskeletal pain, and rare cases of osteonecrosis of the jaw
- Adequate calcium and vitamin D intake should be ensured during therapy
- Regular monitoring by healthcare provider recommended
Common Side Effects:
- Dyspepsia, abdominal pain, nausea
- Muscle or joint pain
- Rare but serious: osteonecrosis of the jaw, atypical femoral fractures
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