Description
Ritban 20mg Tablet is a generic formulation of rivaroxaban, an oral direct Factor Xa inhibitor developed by ATCO Laboratories. It is primarily used in the prevention and treatment of thromboembolic disorders by inhibiting Factor Xa, a key enzyme in the coagulation cascade.
🩺 Indications
Ritban 20mg is indicated for:
- Stroke Prevention: Reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
- Deep Vein Thrombosis (DVT): Treating DVT and preventing its recurrence.
- Pulmonary Embolism (PE): Treating PE and preventing its recurrence.
- Post-Surgery Thrombosis Prevention: Preventing DVT following knee or hip replacement surgery.
- Acute Coronary Syndrome: Reducing the risk of heart attack and stroke in patients with coronary artery disease.
⚙️ Mechanism of Action
Rivaroxaban selectively inhibits Factor Xa, disrupting the conversion of prothrombin to thrombin, thereby preventing the formation of fibrin clots. This targeted action distinguishes rivaroxaban from other anticoagulants, providing a specific and controlled approach to anticoagulation therapy.
💊 Dosage & Administration
- Stroke Prevention: One 20mg tablet once daily with the evening meal.
- DVT/PE Treatment: One 15mg tablet twice daily for the first 3 weeks, then one 20mg tablet once daily.
- Post-Surgery Thrombosis Prevention: Dosage as per doctor’s recommendation.
Take Ritban 20mg with food to enhance absorption. If you have difficulty swallowing tablets, consult your doctor for alternative administration methods.
⚠️ Contraindications
Do not use Ritban 20mg if you:
- Have active or uncontrolled bleeding disorders.
- Are allergic to rivaroxaban or any of its components.
- Have severe liver disease or end-stage kidney disease.
- Are pregnant or breastfeeding.
- Have recently undergone surgery involving the brain, spine, or eyes.
- Are taking other anticoagulants or certain antiplatelet agents unless advised by a doctor.
⚠️ Warnings & Precautions
- Bleeding Risk: Increased risk of bleeding, including serious conditions like intracranial or gastrointestinal bleeding.
- Renal Impairment: Dosage adjustments may be necessary for patients with kidney problems.
- Liver Disease: Use with caution; monitor liver function regularly.
- Spinal Procedures: Risk of spinal or epidural hematoma, especially in patients undergoing spinal procedures.
- Drug Interactions: Avoid concomitant use with strong CYP3A4 and P-glycoprotein inhibitors or inducers.
💊 Side Effects
Common side effects may include:
- Increased risk of bleeding (e.g., nosebleeds, gum bleeding, unusual bruising).
- Headache.
- Dizziness.
- Nausea or vomiting.
- Stomach pain.
- Skin rash or itching.
Serious side effects require immediate medical attention and include signs of severe bleeding, such as:
- Unusual tiredness or weakness.
- Pink or dark urine.
- Coughing up blood.
- Vomiting blood or material that looks like coffee grounds.
- Severe headache or dizziness.
- Vision changes.
- Confusion.
- Trouble speaking.
- Weakness on one side of the body.
🛡️ Storage & Disposal
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not use after the expiration date.
- Dispose of unused or expired medication properly; consult a pharmacist for guidance.
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