Description
SAMCLOM 50mg Tablet (Clomiphene Citrate) is a non-steroidal fertility medication used to stimulate ovulation in women experiencing infertility due to conditions such as polycystic ovary syndrome (PCOS) or unexplained anovulation. By increasing the release of hormones necessary for ovulation, SAMCLOM enhances the chances of conception.
𩺠Indications
SAMCLOM 50mg Tablet is prescribed for:
- Inducing ovulation in women with anovulatory infertility.
- Treating infertility associated with polycystic ovary syndrome (PCOS).
- Assisting in conception for women with unexplained infertility.
âď¸ Mechanism of Action
Clomiphene citrate, the active ingredient in SAMCLOM, works by blocking estrogen receptors in the hypothalamus, leading to an increase in the secretion of gonadotropins (LH and FSH) from the pituitary gland. This stimulation promotes the maturation and release of eggs from the ovaries, facilitating ovulation.
đ Dosage and Administration
- Initial Dose: 50 mg (1 tablet) daily for 5 days, typically starting on the 5th day of the menstrual cycle.
- Adjustment: If ovulation does not occur after the first course, the dose may be increased to 100 mg daily for 5 days.
- Maximum Duration: Treatment is usually limited to 3 courses.
- Always follow your healthcare provider’s instructions regarding dosage and duration.
â ď¸ Precautions
- Not for Use During Pregnancy: SAMCLOM should not be taken if you are pregnant.
- Liver Function: Use with caution in individuals with liver disease.
- Ovarian Cysts: Avoid use if you have ovarian cysts not related to PCOS.
- Endometrial Conditions: Use cautiously if you have endometrial abnormalities.
- Multiple Pregnancies: SAMCLOM increases the likelihood of multiple births, such as twins or triplets.
đ Side Effects
Common side effects may include:
- Hot flashes
- Breast tenderness
- Nausea or vomiting
- Headache
- Abnormal vaginal bleeding
- Visual disturbances (e.g., blurred vision, flashes of light)
Serious side effects are rare but can include ovarian hyperstimulation syndrome (OHSS), which may cause abdominal pain, bloating, nausea, vomiting, and rapid weight gain. Seek immediate medical attention if these symptoms occur.
đĄď¸ Warnings
- Vision Changes: SAMCLOM may cause temporary visual disturbances. Avoid activities requiring clear vision, such as driving, until you know how the medication affects you.
- Ovarian Hyperstimulation Syndrome (OHSS): Monitor for symptoms of OHSS, especially after the first treatment cycle.
- Long-Term Use: Extended use beyond the recommended cycles may increase the risk of ovarian cancer. Consult your healthcare provider for guidance.
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