Description
Description
Propranolol is a non-selective beta-blocker, meaning it blocks both beta-1 and beta-2 adrenergic receptors in the body. Propranolol blocks beta-1 receptors in the heart, which slows down the heart rate and reduces the force of heart contractions. This lowers blood pressure and reduces the heart’s workload. By blocking beta-2 receptors, it can cause narrowing of the airways (bronchoconstriction) and may also cause blood vessels to constrict. This is why it’s used cautiously in people with asthma or other respiratory conditions.
Ingredients
Propranolol
Drug Class
Beta-Blocker
Dosage Form
Tablet
Uses
This tablet is used to manage:
High Blood Pressure
Angina
Arrhythmias
Heart Rate Reduction
Dosage
Propranolol dosage recommendations for Adults are:
High Blood Pressure (Hypertension) – 160-640 mg daily
Chest Pain (Angina) – 80-480 mg daily
Heart Disorders (Obstructive Hypertrophic Cardiomyopathy) – 30-160 mg daily
Irregular Heartbeats (Arrhythmias) – 30-240 mg daily
Protection After Myocardial Infarction – 160 mg daily
Migraine Prevention – 80-240 mg daily
Tremors – 40-160 mg daily
Anxiety Symptoms – 30-160 mg daily
Thyroid Disorders (Thyrotoxicosis) – 30-160 mg daily
Pheochromocytoma – 30-160 mg daily
Prevention of Esophageal Bleeding (High Blood Pressure in the Liver) – 80-320 mg daily
In case of Overdose
In case of overdose or accidental ingestion, immediately consult your doctor or pharmacist, indicating the medication and the amount ingested. It is recommended that you take the pack and package leaflet of this medicine to the healthcare personnel.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is close to the next dose, skip the missed dose. Do not take double doses.
How To Use
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
When Not to Use
Do not take Propranolol if you:
Are allergic (hypersensitive) to propranolol or any of the other ingredients
Suffer from asthma, wheezing, or other breathing difficulties
Have or have ever had heart problems, including heart failure or heart block, or have had a very slow or irregular heart rate, low blood pressure (hypotension), or poor blood circulation
Suffer from Prinzmetal’s angina (a tight, painful feeling in the chest at rest)
Have untreated pheochromocytoma (high blood pressure due to a tumor near the kidney)
Are on a strict fasting diet
Have had a shock caused by heart problems or heart rhythm-related illness (sick sinus syndrome)
Are prone to low blood sugar levels
Are pregnant, think you may be pregnant, or are breastfeeding
Side Effects
The side effects of Propranalol tablets are as follows:
Fatigue
Dizziness
Bradycardia
Gastrointestinal discomfort
Cold extremities
Precautions & Warnings
Here are some crucial warnings and precautions to keep in mind:
Patients with 1st-degree heart block, compensated heart failure, diabetes mellitus, myasthenia gravis, or a history of anaphylactic reactions to allergens should use the medication with caution, as it may impact these conditions.
Those with less severe peripheral circulatory disturbances or Wolff-Parkinson-White Syndrome should also be monitored carefully.
Individuals undergoing surgery should avoid abrupt withdrawal of the medication, especially if they have ischaemic heart disease. Chronic therapy should not be routinely stopped before major surgery.
The medication may mask the signs and symptoms of hypoglycaemia and hyperthyroidism, particularly tachycardia.
It is important to use the medication cautiously in patients with renal and hepatic impairment.
Special care should be taken for neonates, children, and elderly patients. Consult a healthcare provider before use during pregnancy and lactation.
Drug Interactions
Drug interactions with propranolol include:
Antihypertensives (e.g., ACE inhibitors, diuretics) (may enhance the hypotensive effect)
Calcium channel blockers (e.g., verapamil, diltiazem) (may increase the risk of bradycardia and heart block)
CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) (may increase propranolol levels)
NSAIDs (e.g., ibuprofen) (may reduce the antihypertensive effect of propranolol)
Antidiabetic medications (e.g., insulin, metformin) (propranolol may mask hypoglycemic symptoms)
Digoxin (may enhance the effect of propranolol)
Storage/Disposal
Store at room temperature in a tightly closed container. Dispose of unused or expired medication by returning it to a pharmacy for safe disposal.
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