INDERAL 10MG TAB 50S

70.20

Description 

Propranolol is a non-selective beta-blocker, meaning it blocks both beta-1 and beta-2 adrenergic receptors in the body. Propranolol blocks beta-1 receptors in the heart, which slows down the heart rate and reduces the force of heart contractions. This lowers blood pressure and reduces the heart’s workload. By blocking beta-2 receptors, it can cause narrowing of the airways (bronchoconstriction) and may also cause blood vessels to constrict. This is why it’s used cautiously in people with asthma or other respiratory conditions. 

 

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Description

Description 

Propranolol is a non-selective beta-blocker, meaning it blocks both beta-1 and beta-2 adrenergic receptors in the body. Propranolol blocks beta-1 receptors in the heart, which slows down the heart rate and reduces the force of heart contractions. This lowers blood pressure and reduces the heart’s workload. By blocking beta-2 receptors, it can cause narrowing of the airways (bronchoconstriction) and may also cause blood vessels to constrict. This is why it’s used cautiously in people with asthma or other respiratory conditions. 

Ingredients 

Propranolol 

Drug Class 

Beta-Blocker 

Dosage Form 

Tablet 

Uses 

This tablet is used to manage: 

High Blood Pressure 

Angina 

Arrhythmias 

Heart Rate Reduction 

Dosage 

Propranolol dosage recommendations for Adults are: 

High Blood Pressure (Hypertension) – 160-640 mg daily 

Chest Pain (Angina) – 80-480 mg daily 

Heart Disorders (Obstructive Hypertrophic Cardiomyopathy) – 30-160 mg daily 

Irregular Heartbeats (Arrhythmias) – 30-240 mg daily 

Protection After Myocardial Infarction – 160 mg daily 

Migraine Prevention – 80-240 mg daily 

Tremors – 40-160 mg daily 

Anxiety Symptoms – 30-160 mg daily 

Thyroid Disorders (Thyrotoxicosis) – 30-160 mg daily 

Pheochromocytoma – 30-160 mg daily 

Prevention of Esophageal Bleeding (High Blood Pressure in the Liver) – 80-320 mg daily 

In case of Overdose 

In case of overdose or accidental ingestion, immediately consult your doctor or pharmacist, indicating the medication and the amount ingested. It is recommended that you take the pack and package leaflet of this medicine to the healthcare personnel. 

Missed Dose 

If you miss a dose, take it as soon as you remember. If it is close to the next dose, skip the missed dose. Do not take double doses. 

How To Use 

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. 

When Not to Use 

Do not take Propranolol if you: 

Are allergic (hypersensitive) to propranolol or any of the other ingredients 

Suffer from asthma, wheezing, or other breathing difficulties 

Have or have ever had heart problems, including heart failure or heart block, or have had a very slow or irregular heart rate, low blood pressure (hypotension), or poor blood circulation 

Suffer from Prinzmetal’s angina (a tight, painful feeling in the chest at rest) 

Have untreated pheochromocytoma (high blood pressure due to a tumor near the kidney) 

Are on a strict fasting diet 

Have had a shock caused by heart problems or heart rhythm-related illness (sick sinus syndrome) 

Are prone to low blood sugar levels 

Are pregnant, think you may be pregnant, or are breastfeeding 

Side Effects 

The side effects of Propranalol tablets are as follows: 

Fatigue 

Dizziness 

Bradycardia 

Gastrointestinal discomfort 

Cold extremities 

Precautions & Warnings 

Here are some crucial warnings and precautions to keep in mind: 

Patients with 1st-degree heart block, compensated heart failure, diabetes mellitus, myasthenia gravis, or a history of anaphylactic reactions to allergens should use the medication with caution, as it may impact these conditions. 

Those with less severe peripheral circulatory disturbances or Wolff-Parkinson-White Syndrome should also be monitored carefully. 

Individuals undergoing surgery should avoid abrupt withdrawal of the medication, especially if they have ischaemic heart disease. Chronic therapy should not be routinely stopped before major surgery. 

The medication may mask the signs and symptoms of hypoglycaemia and hyperthyroidism, particularly tachycardia. 

It is important to use the medication cautiously in patients with renal and hepatic impairment. 

Special care should be taken for neonates, children, and elderly patients. Consult a healthcare provider before use during pregnancy and lactation. 

Drug Interactions 

Drug interactions with propranolol include: 

Antihypertensives (e.g., ACE inhibitors, diuretics) (may enhance the hypotensive effect) 

Calcium channel blockers (e.g., verapamil, diltiazem) (may increase the risk of bradycardia and heart block) 

CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) (may increase propranolol levels) 

NSAIDs (e.g., ibuprofen) (may reduce the antihypertensive effect of propranolol) 

Antidiabetic medications (e.g., insulin, metformin) (propranolol may mask hypoglycemic symptoms) 

Digoxin (may enhance the effect of propranolol) 

Storage/Disposal 

Store at room temperature in a tightly closed container. Dispose of unused or expired medication by returning it to a pharmacy for safe disposal. 

 

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